On Wednesday, Shares of Corbus Pharmaceuticals Holdings, Inc. (NASDAQ:CRBP), skyrocketed 34.41% to $2.50.
Corbus Pharmaceuticals Holdings declared that the U.S. Food and Drug Administration (“FDA”) has designated as a Fast Track development program the investigation of Resunab™ for systemic sclerosis.
Systemic sclerosis is a serious, life-threatening autoimmune disease that is characterized by chronic activation of the immune system, damage to blood vessels, and fibrosis (scarring) of the skin, lungs, and other internal organs. Systemic sclerosis affects predominately women in mid-life and is associated with noteworthy morbidity and mortality. There are presently no FDA-approved drug therapies for systemic sclerosis.
Resunab is a novel synthetic oral endocannabinoid-mimic drug that preferentially binds to a receptor called CB2 on immune cells and fibroblasts. Numerous pre-clinical and ex-vivo models have demonstrated that the binding of Resunab to CB2 triggers the production of “Specialized Pro-resolving Lipid Mediators” (“SPMs”) that activate an endogenous cascade responsible for the resolution of inflammation and fibrosis. This resolution cascade restores chronically activated immune systems back to homeostasis and halts fibrosis, without causing immunosuppression.
Corbus Pharmaceuticals Holdings, Inc., a clinical stage pharmaceutical company, focuses on the development and commercialization of novel therapeutics to treat rare life-threatening inflammatory and fibrotic diseases.
Shares of Transocean Ltd. (NYSE:RIG), declined -2.99% to $13.65, during its last trading session.
Transocean issued a monthly Fleet Update Summary, which comprises new contracts, changes to existing contracts, and changes in estimated planned out-of-service time of 15 or more days since the July 15, 2015 Fleet Status Report. The total value of new contracts since the last report is about $35 million.
The report comprises the following:
- Dhirubhai Deepwater KG2 - Awarded a contract extension for about three months offshore India at a dayrate of $295,000 ($25 million estimated backlog).
- Transocean Barents - Awarded a one well extension in the Norwegian North Sea at a dayrate of $300,000 ($10 million estimated backlog).
- The Sedco Express, GSF Rig 135, Actinia, Transocean Searcher and Transocean Prospect are idle.
Transocean Ltd., together with its auxiliaries, provides offshore contract drilling services for oil and gas wells worldwide. The company primarily offers deepwater and harsh environment drilling services.
Finally, Brocade Communications Systems, Inc. (NASDAQ:BRCD), ended its last trade with 0.40% gain, and closed at $10.04.
Brocade Communications Systems declared it has expanded the company’s OEM relationship with Lenovo, one of the world’s largest technology companies that significantly raised its enterprise IT infrastructure offerings following the acquisition of IBM’s x86 server business in October 2014.
Brocade Gen 5 Fibre Channel storage area networking (SAN) switches are now being sold globally by Lenovo and its network of channel partners, in addition to embedded Fibre Channel and VCS Ethernet fabric switches that are accessible in solutions for all Lenovo x86-based servers. Brocade fixed-port SAN switches integrate flawlessly into Lenovo’s server and storage solutions, counting the recently declared Lenovo Storage S2200 and S3200 SAN arrays. Additionally, the Brocade switches have accomplished qualification testing for seamless interoperability with these new storage offerings.
Brocade SAN switches deliver the industry’s highest levels of throughput that enable maximum application performance by eliminating network bottlenecks. Brocade SAN switches also comprise Brocade Fabric Vision technologies, which maximize uptime, dramatically simplify SAN deployment and administration, while also providing unprecedented levels of visibility and insight into the storage network.
Brocade Communications Systems, Inc. provides storage area networking (SAN) and Internet protocol networking solutions for businesses and organizations worldwide. It operates through SAN Products, IP Networking Products, and Global Services segments.
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