On Wednesday, Shares of Merck & Co., Inc (NYSE:MRK), gain 0.86% to $52.98.
Merck (MRK), known as MSD outside the United States and Canada, declared that the U.S. Food and Drug Administration (FDA) has approved a supplemental New Drug Application (sNDA) for EMEND® (aprepitant) capsules, a substance P/neurokinin 1 (NK1) receptor antagonist. With this expanded indication, EMEND capsules are now approved for use in combination with other antiemetic agents in patients 12 years of age and older and patients less than 12 years who weigh at least 30 kg (about 66 pounds) for the prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of highly emetogenic cancer chemotherapy (HEC) counting high-dose cisplatin, in addition to for the prevention of nausea and vomiting associated with initial and repeat courses of moderately emetogenic cancer chemotherapy (MEC). EMEND has not been studied for treatment of established nausea and vomiting. Chronic continuous administration of EMEND is not recommended because it has not been studied, and because the drug interaction profile may change during chronic continuous use.
With this approval, EMEND is the first and only NK1 receptor antagonist to be approved for the prevention of acute and delayed phases of chemotherapy-induced nausea and vomiting (CINV) in patients 12 to 17 years of age and patients less than 12 years who weigh at least 30 kg receiving HEC or MEC. The approval was supported by data from a pivotal Phase 3 study that showed adding EMEND to a standard regimen for prevention of CINV in HEC or MEC regimens resulted in a reduction of emetic events.
EMEND is contraindicated in patients with any known sensitivity to any component of this drug. EMEND is also contraindicated for patients taking pimozide.
Merck & Co., Inc. provides health care solutions worldwide. The company offer therapeutic and preventive agents to treat cardiovascular, type 2 diabetes, asthma, nasal allergy symptoms, allergic rhinitis, chronic hepatitis C virus, HIV-1 infection, fungal infections, intra-abdominal infections, hypertension, arthritis and pain, inflammatory, osteoporosis, male pattern hair loss, and fertility diseases.
Shares of FirstEnergy Corp (NYSE:FE), declined -0.39% to $30.86, during its last trading session.
As part of its ongoing efforts to strengthen the durability of its electric system and enhance service reliability for its customers, Potomac Edison, a FirstEnergy Corp. (FE) utility, is proactively replacing about 22 miles of underground distribution cable throughout its Maryland service area at a cost of about $4.5 million.
Much of the cable replacement work is being done in residential subdivisions that were built years ago using an underground electric system instead of using overhead wires.
“We are replacing sections of underground cable in areas where outages have occurred with new wires encased in PVC conduit to better protect the equipment,” said James A. Sears, Jr., FirstEnergy’s president of Maryland Operations and vice president of Potomac Edison. “While underground electrical equipment is in many ways better protected from the elements than overhead wires, if an outage does occur it often takes longer for our crews to pinpoint where the underground problem is and make repair.”
Rather than digging trenches through yards and driveways when replacing underground cable, utility contractors often use specialized equipment to bore horizontally beneath the ground. The equipment is able to change direction underground and bore laterally as far as 500 feet without surfacing, depending on soil composition. Once the boring is accomplished, the conduit and cable are fed through the underground openings.
While underground electric equipment is not exposed to tree-related damage, lightning strikes on interconnected overhead equipment and other conditions can still cause outages. Underground cables housed in conduit are easier for line crews to repair, which can shorten the duration of service interruptions.
FirstEnergy Corp., through its auxiliaries, generates, transmits, and distributes electricity in the United States. The company operates through Regulated Distribution, Regulated Transmission, and Competitive Energy Services segments. It owns and operates fossil, coal-fired, nuclear, oil and natural gas, wind and solar power, and hydroelectric generating facilities.
Finally, Rambus Inc (NASDAQ:RMBS), ended its last trade with 2.42% gain, and closed at $13.56.
Rambus Inc, declared that Dr. Ronald Black, chief executive officer, and Satish Rishi, chief financial officer, will present at the Citi 2015 Global Technology Conference in New York on Wednesday, September 9, 2015.
Rambus Inc. operates as a technology solutions company in South Korea, the United States, Japan, Europe, Canada, Asia, and internationally. The companys technology solutions comprise memory, chip interfaces and architectures, end-to-end security, and advanced LED lighting.
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