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Saturday 11 July 2015
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Bears of the Day: Neurocrine Biosciences, (NASDAQ:NBIX), Advaxis, (NASDAQ:ADXS), Viggle (NASDAQ:VGGL), Merrimack Pharmaceuticals (NASDAQ:MACK)

On Monday, Neurocrine Biosciences, Inc. (NASDAQ:NBIX)’s shares declined -8.92% to $39.50.

Neurocrine Biosciences, Inc. (NBIX) declared that the Company will report its first quarter 2015 results before the Nasdaq market opens on Thursday, April 30, 2015. Neurocrine will then host a live conference call and webcast to talk about its financial results and provide a Company update Thursday morning, April 30, 2015 at 8:00 a.m. Eastern Time (5:00 a.m. Pacific Time).

Neurocrine Biosciences, Inc. discovers and develops pharmaceuticals for the treatment of neurological and endocrine-related diseases and disorders in the United States.

Advaxis, Inc. (NASDAQ:ADXS)’s shares dropped -8.83% to $21.28.

ADXS31-164 is a novel Lm-LLO immunotherapy developed by Advaxis, Inc. (ADXS) to target HER2 receptor expressing cancers. In March 2014, Aratana licensed ADXS31-164 from Advaxis for the treatment of canine osteosarcoma and other cancers, adding the drug product to its pipeline of cancer therapeutics as AT-014.

On Monday, April 20, Nicola J. Mason, BVetMed, Ph.D., DACVIM, Assistant Professor of Medicine, University of Pennsylvania’s School of Veterinary Medicine, presented preliminary data from an ongoing Phase 1 clinical study of 10 companion dogs with osteosarcoma (Poster Board #7; Abstract #LB-113). The data suggests that ADXS31-164 in combination with palliative radiation delayed tumor progression and prolonged overall survival in pet dogs with spontaneous osteosarcoma that were not candidates for primary tumor removal (amputation). Repeat doses of ADXS-HER2 were well tolerated with no systemic or cardiac toxicity. Additionally, the combination treatment was found to maintain or improve limb function and quality of life over the study period. Five of the treated dogs remain alive, with a median survival, to date, of all 10 study dogs stated at 285 days, which compares favorably to historical median survival time of 136 days in dogs treated with palliative radiation only.

Advaxis, Inc., a clinical stage biotechnology company, focuses on the discovery, development, and commercialization of Lm-LLO cancer immunotherapies in the United States.

At the end of Monday’s trade, Viggle Inc (NASDAQ:VGGL)‘s shares dipped -8.63% to $2.33.

Viggle Inc (VGGL) the entertainment marketing and rewards platform, has planned a conference call on Monday, May 11, 2015 at 9:00 A.M. Eastern Time (ET) to review results for the fiscal 2015 third quarter ended March 31, 2015.

Viggle Inc. operates as a mobile and Web-based entertainment marketing platform for media companies, brands, and consumers in the United States. It guides users towards various forms of media consumption with television enhancement, music discovery, entertainment content publishing, and distributed viewing reminders.

Merrimack Pharmaceuticals Inc (NASDAQ:MACK), ended its Monday’s trading session with -8.53% loss, and closed at $12.27.

Merrimack Pharmaceuticals Inc (MACK) and Baxter International Inc. (BAX) recently jointly declared that Merrimack has accomplished the rolling submission of the New Drug Application (NDA) for MM-398 (irinotecan liposome injection), also known as “nal-IRI,” to the U.S. Food and Drug Administration (FDA). Merrimack is seeking U.S. marketing approval of MM-398 for the treatment of patients with metastatic adenocarcinoma of the pancreas who have been formerly treated with gemcitabine-based therapy. The companies also declared that Merrimack has requested precedingity review of the MM-398 NDA by the FDA.

Merrimack Pharmaceuticals, Inc., a biopharmaceutical company, engages in discovering, developing, and preparing to commercialize medicines paired with companion diagnostics for the treatment of cancer primarily in the United States.

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