On Wednesday, Shares of AEterna Zentaris Inc. (USA) (NASDAQ:AEZS), lost -7.37% to $0.0880.
AEterna Zentaris declared that its lead oncology compound, zoptarelin doxorubicin (formerly AEZS‑108), met the primary end-point of the investigator-driven and sponsored Phase 2 clinical trial in Castration and taxane Resistant Prostate Cancer (CRPC) and demonstrated good tolerability. The primary endpoint was Clinical Benefit (CB) defined as remaining progression-free by RECIST and Prostate Specific Antigen (PSA) after treatment for 12+ weeks.
Results were presented this morning by lead investigator, Jacek Pinski , MD, PhD, of the USC Norris Comprehensive Cancer Center, during a poster session at the 18th ECCO – 40th ESMO European Cancer Congress in Vienna, Austria .
David A. Dodd , Chairman and CEO of Aeterna Zentaris, commented, “We are encouraged with the Phase 2 results for zoptarelin doxorubicin in prostate cancer. Because luteinizing hormone-releasing hormone receptors are expressed in a great number of cancers counting prostate cancer, we believe that zoptarelin doxorubicin, which specifically targets those receptors, may represent a novel targeted treatment for men with this disease. These Phase 2 results in prostate cancer, in addition to prior positive Phase 2 results in endometrial and ovarian cancer, are further demonstration of the potential of this innovative compound in a variety of cancer indications for both men and women.”
Aeterna Zentaris Inc. is a Canada-based specialty biopharmaceutical company engaged in developing treatments in oncology, endocrinology and women’s health. The Company has three wholly owned direct and indirect subsidiaries: AEZS GmbH, based in Frankfurt, Germany, Zentaris IVF GmbH, a direct wholly owned subsidiary of AEZS Germany based in Frankfurt, Germany, and Aeterna Zentaris, Inc.
Shares of CSX Corporation (NYSE:CSX), inclined 3.66% to $26.89, during its last trading session.
CSX Corporation and two leading mechanical unions, the International Association of Machinists and Aerospace Workers (IAM) and the International Association of Sheet Metal, Air, Rail and Transportation Workers (SMART), recently declared a landmark partnership that will enhance benefits for CSX employees and further improve productivity.
“This agreement is part of CSX’s focus on promoting a flexible workforce to meet changing business demands, and developing opportunities to retain and support our highly skilled workforce,” said Cressie Brown, vice president-labor relations, CSX.
Under the tentative agreement, which is being presented for ratification, members of the IAM and SMART unions will be able to perform a variety of assigned work beyond the traditional boundaries of craft or union affiliation. Covered employees will see raised pay through an hourly skill differential, improved ability to retain employment, benefits and connection to railroad retirement and an ability to perform additional locomotive rebuild work in-house with CSX employees. This new agreement builds on the success of a similar work-sharing structure implemented at the company’s Huntington Locomotive Shop in 2013.
CSX Corporation (CSX), together with its subsidiaries, is a transportation company. The Company provides rail-based transportation services, including traditional rail service and the transport of intermodal containers and trailers. The Company has three lines of business: merchandise business, coal business and the intermodal business.
Shares of Activision Blizzard, Inc. (NASDAQ:ATVI), inclined 0.75% to $30.89, during its last trading session.
Activision Blizzard - With the forthcoming release of Call of Duty®: Black Ops III, the sequel to the best-selling series in Call of Duty® history, eSports is poised to expand to new audiences, while introducing new ways for fans of all skill levels to join the eSports movement. Activision Publishing, Inc., a wholly owned partner of Activision Blizzard (Nasdaq: ATVI), and Call of Duty declared recently the creation of the Call of Duty® World League, a worldwide eSports league by Activision in support of the #1 console eSports franchise, Call of Duty. The new league marks an unprecedented commitment by Call of Duty and its dedicated eSports team to directly support the growing community of eSports fans. The program will provide a deeper level of engagement with the elite circuit of professional gamers, while also encouraging casual fans and aspiring competitors of Call of Duty to enjoy the thrill of competition across different skill levels.
“Call of Duty has always been about community, camaraderie and competition, which drives incredible engagement with the game all year long. eSports allows us to deliver these moments to our fans whether they are playing the game themselves or cheering on those who are,” said Eric Hirshberg, CEO of Activision Publishing, Inc. “Three years ago, we held the first Call of Duty Championship to showcase the dedication and skill of Call of Duty players around the world. Since then, eSports has become a global phenomenon with more than 120 million people watching online competitive gaming each year and Call of Duty continues to lead as the top console eSports franchise in the world.”
Activision Blizzard, Inc. is a developer and publisher of online, personal computer (PC), video game console, handheld, mobile and tablet games. The Company offers games that operate on the Microsoft Corporation (Microsoft) Xbox One (Xbox One) and Xbox 360 (Xbox 360), Nintendo Co.
Finally, Alcatel Lucent SA (ADR) (NYSE:ALU), ended its last trade with 3.99% gain, and closed at $3.65.
Alcatel Lucent is to introduce a new series of IP routers that will give service providers and enterprises an economically and ergonomically optimized platform for smaller locations in large-scale IP networks, or as a full-service router for smaller networks.
The new 7750 SR-e service router will expand Alcatel-Lucent’s highly successful 7750 Service Router (SR) family, extending the benefits of service routing further into the network to give service providers and enterprises IP routing technology scaled to their needs at different network locations.
Communications networks recently are advancing at an unprecedented pace to adapt to the shift in cloud-based operations, the emerging Internet of Things, ultra-high definition video and the ongoing demand for bandwidth. Residential and mobile users are also gaining higher speed access through technologies such as Fiber-to-the-Home, Wi-Fi, LTE and LTE-Advanced.
These events are putting noteworthy pressure on aggregation networks and on the network service edge. In turn, operators are being driven to push edge service functions out from a few large, centralized sites to a more distributed architecture with many smaller locations.
Alcatel Lucent is a provider of Internet protocol (IP) and cloud networking and ultra-broadband access. The Company operates through Core Networking and Access segments. The Company’s Core Networking segment includes IP Routing, comprised of its IP routing portfolio and Nuage Networks; IP Transport, comprised of its terrestrial optics, submarine optics and wireless transmission portfolios, and IP Platforms, which includes software as well as services.
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