On Wednesday, Shares of Novavax, Inc. (NASDAQ:NVAX), gained 10.45% to $7.08.
Novavax declared positive top-line data from a Phase 1 clinical trial of its RSV F-protein recombinant nanoparticle vaccine candidate (RSV F Vaccine) in healthy children.
The trial was a randomized, observer-blinded, Phase 1 study to evaluate the safety and immunogenicity of the RSV F Vaccine, with one or two doses, with or without aluminum phosphate adjuvant, in healthy pediatric participants two to six years of age. The trial’s primary aim was to evaluate safety in this population and immunogenicity as measured by concentrations of serum IgG antibodies to the RSV fusion, or F-protein, palivizumab-competing antibody (PCA) titers and RSV microneutralization titers. Novavax concluded this trial’s enrollment with a smaller than planned cohort so dosing could be accomplished ahead of the 2014-2015 RSV season.
Of the 32 total children enrolled, serum samples were collected from a subset of 18 children in the per-protocol population at 14, 28 and 56 days. All RSV F Vaccine formulations and regimens were well-tolerated and highly immunogenic. Consistent with prior trials, anti-F IgG and PCA titers raised rapidly at day 14, peaked at day 28 and remained at elevated levels through day 56; the last time point presently analyzed. There were greater than 10-fold improvements in both anti-F IgG and PCA antibody titers in the adjuvanted group and greater than 6-fold improvements in anti-F IgG and PCA antibody titers in the unadjuvanted group.
Novavax, Inc. (Novavax) is a clinical-stage vaccine company engaged in the discovery, development and commercialization of recombinant nanoparticle vaccines and adjuvants. The Company through its recombinant nanoparticle vaccine technology produces vaccine candidates to respond to both known and newly emerging diseases.
Shares of Marathon Oil Corporation (NYSE:MRO), inclined 2.87% to $15.40, during its last trading session.
Marathon Oil Corporation declared recently that Gaurdie E. Banister, Jr., has been elected to the Company’s board of directors, effective Oct. 1, 2015.
Banister, 57, recently stepped down after serving eight years as president and CEO of Aera Energy LLC, an oil and gas exploration and production company jointly owned by Shell Oil Company and ExxonMobil, headquartered in California. Banister has 35 years of oil and gas experience, and before Aera served in executive level positions at Shell counting technical vice president Upstream Asia Pacific and technical vice president Upstream Americas.
Banister joined Shell Oil in 1980 as an offshore facilities engineer in New Orleans, and throughout his career served in various production administration assignments based in Louisiana, California, Texas and Asia. He became president USA and executive vice president of Shell Services EP Gas and Power in 1998. From 2001 to 2003 Banister served as vice president of Business Development and Technology. In 2003 he was named technical vice president, Upstream Americas and championed innovative capital cost approaches to major projects. From 2005 until 2007 Banister was technical vice president, Upstream Asia Pacific. In this role he oversaw drilling and development activities in Southeast Asia, Australia and New Zealand, and established milestones and processes to safely execute major projects both onshore and offshore.
Marathon Oil Corporation is an energy company based in Houston, Texas, with operations in North America, Europe and Africa. The Company operates in three segments: North America E&P segment, which explores for, produces and markets crude oil and condensate, NGLs and natural gas in North America; International E&P segment, which explores for, produces and markets crude oil and condensate, NGLs and natural gas outside of North America and produces and markets products manufactured from natural gas, such as LNG and methanol, in Egypt and Oil Sands Mining segment, which mines, extracts and transports bitumen from oil sands deposits in Alberta, Canada, and upgrades the bitumen to produce and market synthetic crude oil and vacuum gas oil. It has production operations in the United States, Egypt, Canada, the United Kingdom and Libya.
Shares of Hilton Worldwide Holdings Inc (NYSE:HLT), inclined 4.70% to $22.93, during its last trading session.
With nearly a third (32%) of UK professionals admitting that friends and family describe them as ‘workaholics’1, Hilton Worldwide (HLT) turns its focus to the Capital in its quest to inspire travellers to reclaim fun with its Hilton@PLAY concert series. Following spectacular performances in Chicago, Dallas and New York, Hilton@PLAY will welcome Jess Glynne to the stage on 22nd October at the soon-to-open Hilton London Bankside, Hilton’s newest hotel in the city.
Through the Hilton@PLAY initiative, Hilton and Live Nation are scheduling performances with some of the biggest names in music at Hilton locations throughout the world. To attend the events, members of Hilton HHonors, the loyalty program for Hilton’s 12 distinct hotel brands, are invited to visit HHonors.com/auctions and redeem Hilton HHonors Points.
Geraldine Calpin, global head, marketing and digital, Hilton Worldwide, said, “After hosting three successful Hilton@PLAY concerts at some of our most storied hotels, we’re excited to take a new approach in London, coinciding the concert with the official opening party of Hilton London Bankside. We knew it was time to turn our focus to another city known to work hard, and more importantly, play hard - and with 29 Hilton properties located across the city, London felt like the natural choice. What better way to enjoy the city in all its glory, than by offering an unforgettable performance at our new hotel with chart-topping sensation, Jess Glynne!”
Hilton Worldwide Holdings Inc. is a hospitality company. The Company comprises of approximately 4,322 hotels, resorts and timeshare properties comprising of 715,062 rooms in 94 countries and territories. The Company operates through three segments: management and franchise, ownership and timeshare.
Finally, Metlife Inc (NYSE:MET), ended its last trade with 1.70% gain, and closed at $47.13.
Metlife declared that it, together with New York Life Insurance and Pacific Life, has offered a $1 billion, 12-year fixed rate loan to refinance an existing mortgage on The Mall at Short Hills, a major luxury shopping complex in northern New Jersey owned by Taubman.
MetLife is the lead lender in this transaction, with each insurer taking one-third of the $1 billion loan. The collateral for the loan is the 1.4 million-square-foot enclosed mall, which has major retailers counting Bloomingdale’s, Macy’s, Neiman Marcus, Nordstrom and Saks Fifth Avenue.
Taubman has a portfolio of 19 urban and suburban shopping centers across the United States and the Caribbean.
MetLife, Inc. (MetLife) is a provider of life insurance, annuities, employee benefits and asset management. The Company’s segments include Retail; Group, Voluntary & Worksite Benefits, and Corporate Benefit Funding. Its three geographic segments are Latin America (collectively, the Americas); Asia, and Europe, the Middle East and Africa (EMEA).
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