On Wednesday, Shares of Pfizer Inc. (NYSE:PFE), gained 0.88% to $34.31.
Pfizer, declared that more than 20 abstracts counting new rheumatoid arthritis (RA) research for XELJANZ® (tofacitinib citrate) will be presented at the European League Against Rheumatism Annual Congress (EULAR 2015) June 10-15, Rome, Italy. Highlights comprise over six-years of safety and efficacy data from two long-term extension studies, real-world experience analyses, and clinical, patient-stated and radiographic efficacy outcomes with XELJANZ monotherapy, in addition to health economics outcomes research that comprise patient-preference data for XELJANZ in patients with RA. Notably, new results from the XELJANZ 11 mg once daily clinical pharmacology program will be presented during the Congress, demonstrating equivalence in key pharmacokinetic parameters to XELJANZ 5 mg twice daily.
“As the developer of XELJANZ, the first oral Janus kinase inhibitor for the treatment of moderate to severe RA, Pfizer is a leader in the research of this new class of medications. Emerging real-world experience complements the clinical profile of XELJANZ as established through our extensive global development program,” said Rory O’Connor, MD, senior vice president and head of Global Medical Affairs, Global Innovative Pharmaceuticals Business, Pfizer Inc. “We continue to focus on further characterizing the overall clinical profile of XELJANZ that comprises understanding the response of XELJANZ as monotherapy and by exploring a potential new once-daily formulation.”
Pfizer Inc., a biopharmaceutical company, discovers, develops, manufactures, and sells healthcare products worldwide. The company operates through Global Innovative Pharmaceutical (GIP); Global Vaccines, Oncology and Consumer Healthcare (VOC); and Global Established Pharmaceutical (GEP) segments.
Shares of Johnson & Johnson (NYSE:JNJ), inclined 0.68% to $98.88, during its last trading session.
On May 28, Johnson & Johnson declared the acceptance of the March 1, 2015 binding offer from Cardinal Health to acquire its Cordis business for an approximate value of $2 billion. The offer was accepted after consultations with relevant works councils and trade unions. The company anticipates the transaction to close towards the end of 2015, subject to regulatory clearances and other customary closing conditions.
Johnson & Johnson remains dedicated to combating cardiovascular disease through its electrophysiology business, Biosense Webster, in the Medical Devices segment and its leading cardiovascular medicine, XARELTO®, in the Pharmaceutical segment.
Johnson & Johnson, together with its auxiliaries, researches and develops, manufactures, and sells various products in the health care field worldwide. It operates in three segments: Consumer, Pharmaceutical, and Medical Devices.
Finally, AbbVie Inc. (NYSE:ABBV), ended its last trade with 0.84% gain, and closed at $68.24.
On June 4, Pharmacyclics LLC, an AbbVie company, declared that ibrutinib (IMBRUVICA®) improved progression-free survival (PFS; primary endpoint) and multiple secondary endpoints counting overall survival (OS) and overall response rate (ORR) in treatment-naïve patients with chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL/SLL, respectively) in the final analysis of the Phase III RESONATE™-2 (PCYC-1115) trial. RESONATE-2 is a randomized, multi-center, open-label study assessing the use of ibrutinib as compared to chlorambucil in treatment-naïve CLL/SLL patients aged 65 years or older. This is the first head-to-head trial in the clinical program that evaluates the safety and efficacy of ibrutinib as compared to traditional chemotherapy. IMBRUVICA is jointly developed and commercialized by Pharmacyclics and Janssen Biotech, Inc.
“In partnership with our partner Janssen, we are very excited by the findings from RESONATE-2 and look forward to sharing the results from what we see as a potentially transformative study for CLL patients,” said Danelle James, M.D., M.S., Head of Oncology at Pharmacyclics. “These results from the first IMBRUVICA study for front-line CLL patients may support future treatment paradigms where some CLL patients requiring therapy may not need to be exposed to traditional cytotoxic chemotherapy.”
“Over the past several years we’ve made tremendous progress in treating CLL, thanks in part to therapies such as IMBRUVICA,” said Richard A. Gonzalez, Chairman of the Board and Chief Executive Officer at AbbVie. “Based on the results from RESONATE-2, IMBRUVICA continues to demonstrate its strong value and we are very optimistic that it will eventually move into the front-line treatment setting, becoming an alternative option to chemotherapy for formerly untreated CLL patients.”
AbbVie Inc. discovers, develops, manufactures, and sells pharmaceutical products worldwide. The company’s products comprise HUMIRA, a biologic therapy administered as a subcutaneous injection to treat autoimmune diseases; VIEKIRA PAK, an all-oral, short-course, interferon-free therapy, with or without ribavirin, for adult patients with genotype 1 chronic hepatitis, counting those with compensated cirrhosis.
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