On Friday, Oncothyreon Inc (USA) (NASDAQ:ONTY)’s shares inclined 0.26% to $3.88.
Oncothyreon Inc. (ONTY) declared the presentation of positive data from the company’s ongoing trials of ONT-380, an orally active, reversible and selective small-molecule HER2 inhibitor for the treatment of breast cancer, at the American Society of Clinical Oncology (ASCO) 2015 Annual Meeting. The first presentation updated data from the Phase 1b trial of ONT-380 in combination with Xeloda(R) (capecitabine)and Herceptin(R) (trastuzumab) in third line treatment of HER2-positive metastatic breast cancer. The data support Oncothyreon’s plans to initiate a blinded, randomized, placebo-controlled Phase 2 trial in this indication. The second presentation focused on the role of ONT-380 in the treatment of HER2-positive breast cancer central nervous system (CNS) metastases.
Patients comprised of in the presentation on the role of ONT-380 in the treatment of CNS metastases were selected from the above trial and from an ongoing Phase 1b trial (ClinicalTrials.gov Identifier NCT01983501) of ONT-380 in combination with Kadcyla in patients who have been formerly treated with Herceptin and a taxane for metastatic breast cancer. Patients were comprised of if their presenting CNS lesions were evaluable for response using RECIST 1.1 criteria and they had either untreated, asymptomatic lesions having never received radiotherapy or surgery to the CNS (n=8) or new or progressive lesions following prior CNS therapy (n=14). Best CNS response was a CR in one patient, a PR in four patients and SD in nine patients. No patient had progressive disease as a CNS best response. One patient was not evaluable for response having undergone surgery for a symptomatic CNS lesion; pathologic examination of the resected specimen found no evidence of viable tumor. Two patients were not evaluated because of progressive disease outside of the CNS, while five patients in the series remain too early to evaluate.
Oncothyreon Inc., a clinical-stage biopharmaceutical company, engages in the research and development of therapeutic products for the treatment of cancer. Its clinical-stage product candidates comprise ONT-380, an orally active and selective small-molecule HER2 inhibitor, which is in two Phase 1b trials, one in combination with Kadcyla and another in combination with Xeloda and/or Herceptin; and ONT-10, a therapeutic vaccine in Phase 1 trial targeting the Mucin 1 peptide antigen (MUC1) for use in various cancer indications, counting breast, thyroid, colon, stomach, pancreas, ovarian, and prostate, in addition to certain types of lung cancer.
Cheniere Energy, Inc. (NYSEMKT:LNG)’s shares dropped -1.23% to $71.42.
Cheniere Energy, Inc. (LNG) project developments that, if accomplished, are projected to add up to about 19 million tonnes per annum (“mtpa”) of incremental LNG production capacity and would bring Cheniere’s aggregate nominal LNG production capacity to about 60 mtpa by 2025.
Cheniere is developing about 9 mtpa of incremental LNG production capacity through the addition of two liquefaction trains adjacent to the existing site of the Corpus Christi liquefaction project (the “CCL Project”). Predictable nominal LNG production capacity of each of these liquefaction trains is about 4.5 mtpa, which would enhance the predictable aggregate nominal LNG production capacity at the CCL Project to about 22.5 mtpa. Cheniere initiated the regulatory process in June 2015 by filing the National Environmental Policy Act pre-filing request with the FERC and the FTA and non-FTA approval requests with the DOE. Regulatory approvals would be predictable in 2017.
Cheniere Energy, Inc., an energy company, engages in the liquefied natural gas (LNG) related business. It operates through two segments, LNG Terminal Business, and LNG and Natural Gas Marketing Business. The company owns and operates Sabine Pass LNG terminal in western Cameron Parish, Louisiana; and Corpus Christi LNG terminal near Corpus Christi, Texas.
At the end of Friday’s trade, Mack Cali Realty Corp (NYSE:CLI)‘s shares surged 1.76% to $18.48.
Mack Cali Realty Corp (CLI) declared a new executive leadership team of Mitchell E. Rudin and Michael J. DeMarco. Effective right away, Mr. Rudin will serve as chief executive officer and Mr. DeMarco will serve as president and chief operating officer.
Messrs. Rudin and DeMarco are accomplished industry veterans, each with more than 30 years of experience in real estate. Most recently, Mr. Rudin served as the president and chief executive officer of U.S. Commercial Operations at Brookfield Office Properties and prior to that he served as the president and chief executive officer of the New York Tri-State Region for CBRE, Inc. Mr. DeMarco’s expertise is in the areas of investment banking, capital markets, and restructuring of operations, which comprises his time as a senior managing director at Lehman Brothers, a managing director at Fortress Investment Group, and an executive vice president at Vornado Realty Trust.
Mack-Cali Realty Corporation is a real estate investment trust (REIT). It engages in the leasing, administration, acquisition, development, and construction of commercial real estate properties in the United States. The firm invests in the real estate markets of the United States primarily in the northeastern United States, in addition to in the District of Columbia.
Mobile TeleSystems OJSC (ADR) (NYSE:MBT), ended its Friday’s trading session with -0.64% loss, and closed at $9.37.
Mobile TeleSystems OJSC (ADR) (MBT) declared its unaudited IFRS financial results for the three months ended March 31, 2015.
Key Financial Highlights of Q1 2015
- Merged group revenue raised 2.7% y-o-y to RUB 100.2 bln.
- Total revenue in Russia raised 3.6% y-o-y to RUB 90.4 bln.
- Mobile service revenue in Russia improved 3.9% y-o-y to RUB 70.5 billion.
- Data traffic revenue in Russia grew 26.0% y-o-y to RUB 18.1 bln.
- Handset sales raised 1.2% y-o-y to RUB 6.3 bln.
- Group Adjusted OBDA down 2.0% to RUB 41.3 bln.
- OIBDA in Russia raised 0.9% y-o-y to RUB 38.2 bln.
Key Corporate and Industry Highlights
- Won a tender for a nationwide license for the provision of 3G telecommunications services in the 1950-1965 MHz/2140-2155 MHz in Ukraine. The cost of the license amounted to UAH 2.7 bln.
- Launched LTE network in the 1800 MHz range in Moscow and LTE network in the 800 MHz range throughout the Moscow region.
- Launched LTE network in the 1800 MHz range in Saint Petersburg and the Leningrad Region.
- Launched LTE network in the 1800 MHz range in the Krasnodar region in southern Russia.
- Annual dividend recommendation by the MTS Board of RUB 19.56 per ordinary MTS share (RUB 39.12 per ADR), or a total of RUB 40.419 bln based on the full-year 2014 financial results, upon acceptance by the AGM and completion of this payment, MTS will have paid out up to RUB 53.2 bln rubles based on fiscal year 2014 financial results.
- Signed a USD 200 mln equivalent term loan facility agreement with China Development Bank Corporation (“CDB”) in renminbi and US dollars.
Mr. Alexey Kornya stated that At MTS they have long considered dividends to be a key commitment to their shareholders. This is both a reflection of the strong market, in which they operate, and prudent administration of their business. They are happy that the results of 2014 will allow them to pay out the largest dividend in their history; for the Fiscal Year 2014, MTS will have paid out 53.2 billion rubles. Most importantly, this sum is derived from their free cash flow, which does not require them to resort to outside funding to finance this payment. Unlike some, our view is that a dividend story is best preserved by paying one. And in that respect in April, the Board recommended to the AGM to be held on June 25, 2015, to approve annual dividends of 19.56 rubles per ordinary MTS share, or a total of 40.4 billion rubles, based on the full-year 2014 financial results.
Mobile TeleSystems OJSC provides telecommunication services in Russia and the Commonwealth of Independent States. The company offers a range of mobile and fixed line voice and data telecommunications services, including data transfer, broadband, pay-TV, and various value-added services, as well as sells equipment and accessories.
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