Pre-Market Stocks Update: Vale (NYSE:VALE), Merck (NYSE:MRK), Umpqua Holdings Corp (NASDAQ:UMPQ)

Pre-Market Stocks Update: Vale (NYSE:VALE), Merck (NYSE:MRK), Umpqua Holdings Corp (NASDAQ:UMPQ)

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On Wednesday, Vale SA (ADR) (NYSE:VALE)’s shares inclined 3.45% to $3.44. VALE has beta value stands at 1.39 times and earnings per share was $-0.76. The company has total of 3.19 billion outstanding shares and its total market capitalization is $16.07 million. 52-week price range of the stock remained $2.99 - $9.14.

Vale S.A., together with its auxiliaries, engages in the research, production, and sale of iron ore and pellets, nickel, fertilizer, copper, coal, manganese, ferroalloys, cobalt, platinum group metals, and precious metals in Brazil and internationally. Its Bulk Material segment produces and extracts iron ore and pellet.

Merck & Co., Inc. (NYSE:MRK)’s shares gained 2.12% to $54.02.

Merck (MRK), known as MSD outside the United States and Canada, declared that the U.S. Food and Drug Administration (FDA) approved an expanded age indication for GARDASIL®9 (Human Papillomavirus 9-valent Vaccine, Recombinant), Merck’s 9-valent human papillomavirus (HPV) vaccine, to now comprise use in males 16 through 26 years of age, for the prevention of anal cancer caused by HPV types 16, 18, 31, 33, 45, 52 and 58, precancerous or dysplastic lesions caused by HPV types 6, 11, 16, 18, 31, 33, 45, 52 and 58, and genital warts caused by HPV types 6 and 11. GARDASIL 9 is already approved for use in boys 9 through 15 years of age for the prevention of these diseases. GARDASIL 9 is also approved for use in girls and young women 9 through 26 years of age for the prevention of cervical, vulvar, vaginal, and anal cancers caused by HPV 16, 18, 31, 33, 45, 52 and 58, precancerous or dysplastic lesions caused by HPV 6, 11, 16, 18, 31, 33, 45, 52, and 58, and genital warts caused by HPV types 6 and 11. GARDASIL 9 is contraindicated in individuals with hypersensitivity, counting severe allergic reactions to yeast, or after a previous dose of GARDASIL 9 or GARDASIL® [Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant].

“This is an important approval that now aligns the indication for GARDASIL 9 in males and females ages 9 through 26 to that of GARDASIL, and also supports the CDC’s HPV vaccine recommendations for use in males,” said Jacques Cholat, M.D., president, Merck Vaccines. “We are happy that males 16 through 26 years of age will now have access to GARDASIL 9, which comprises the most HPV types, to assist further reduce the burden of HPV-related diseases.”

GARDASIL 9 (Human Papillomavirus 9-valent Vaccine, Recombinant) comprises the greatest number of HPV types in any accessible HPV vaccine. GARDASIL 9 adds protection against five additional HPV types — 31, 33, 45, 52 and 58 — in addition to the four original HPV types covered by GARDASIL [Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant]. Seven HPV types in GARDASIL 9 (HPV 16, 18, 31, 33, 45, 52 and 58) cause about 90-95 percent of HPV-related anal cancers, about 90 percent of cervical cancers, and about 80 percent of high-grade cervical lesions (cervical precancers, defined as CIN 2 and CIN 3) worldwide. These seven HPV types also cause 90 percent of HPV-related vulvar cancers and 85 percent of HPV-related vaginal cancers. HPV types 6 and 11 cause about 90 percent of genital warts cases in males and females.

Merck & Co., Inc. provides health care solutions worldwide. The company offer therapeutic and preventive agents to treat cardiovascular, type 2 diabetes, asthma, nasal allergy symptoms, allergic rhinitis, chronic hepatitis C virus, HIV-1 infection, fungal infections, intra-abdominal infections, hypertension, arthritis and pain, inflammatory, osteoporosis, male pattern hair loss, and fertility diseases.

At the end of Wednesday’s trade, Umpqua Holdings Corp (NASDAQ:UMPQ)‘s shares surged 1.04% to $16.58.

Umpqua Holdings Corporation (UMPQ) declared that its Board of Directors has approved a quarterly cash dividend in the amount of $0.16 per common share. The dividend is payable on January 15, 2016, to shareholders of record as of December 31, 2015.

Umpqua Holdings Corporation, through its auxiliaries, engages in the commercial and retail banking, and retail brokerage businesses. It operates through two segments, Community Banking and Home Lending.

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