On Wednesday, Shares of Tetraphase Pharmaceuticals, Inc. (NASDAQ:TTPH), lost -78.81% to $9.49, hitting its lowest level.
Tetraphase Pharmaceuticals declared that the IGNITE2 phase 3 clinical trial of eravacycline administered as an IV to oral transition therapy for the treatment of complicated urinary tract infections (cUTI) did not achieve its primary endpoint of statistical non-inferiority contrast to levofloxacin.
“We are disappointed that the IGNITE2 trial did not achieve its primary endpoint. We plan to further analyze the data and provide an update after we have talked about the data and our plans for a path forward with the regulatory agencies,” said Guy Macdonald, President and CEO of Tetraphase. “We formerly declared positive data from the IGNITE1 phase 3 clinical trial of eravacycline administered intravenously in complicated intra-abdominal infections which did meet its primary endpoint, demonstrating high cure rates in prevalent Gram-negative pathogens and a favorable safety profile.”
Macdonald added, “We continue to believe that eravacycline can benefit patients with serious infections, particularly those caused by difficult-to-treat Gram-negative bacteria.”
Tetraphase Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, develops various antibiotics for the treatment of serious and life-threatening multi-drug resistant infections. Its lead product candidate comprises eravacycline, an intravenous and oral antibiotic for use as a first-line empiric monotherapy for the treatment of multidrug-resistant infections, counting multidrug-resistant Gram-negative infections.
Shares of The Kroger Co. (NYSE:KR), declined -1.85% to $34.40, during its last trading session.
The largest-ever Kroger store will open to the public in Greater Cincinnati on Thursday morning, but the Courier got an early look inside, according to American City Business Journals.
The Kroger Marketplace at Oakley Station will open its doors at 8 a.m. Thursday at 4613 Marburg Ave. The $28 million store is the largest the Cincinnati-based grocer (NYSE: KR) has ever built, at 145,000 square feet, and will create 375 jobs. American City Business Journals Reports
The store features murals from local artists, a bulk natural foods center, wine and growler bar, a Little Clinic and a pharmacy with two drive-thru lanes. There is also an area with apparel, a baby center and a kitchen department together with a sushi bar, Starbucks and Murray’s Cheese shop. There’s a separate entrance to a Bistro with grab-and-go foods together with freshly prepared items and a Fred Meyer Jewelers store. American City Business Journals added.
The Kroger Co., together with its auxiliaries, operates as a retailer in the United States and internationally. It also manufactures and processes food for sale in its supermarkets. The company operates retail food and drug stores, multi-department stores, jewelry stores, and convenience stores.
Finally, The Boeing Company (NYSE:BA), ended its last trade with -0.87% loss, and closed at $132.65.
The Boeing Company reports that over the next 20 years the Asia Pacific region will have the greatest demand for commercial airline pilots and maintenance technicians worldwide with about 40 percent of the global need — more than North America, Africa and Europe combined.
The 2015 Boeing Pilot & Technician Outlook, an industry forecast of aviation personnel demand, anticipates 226,000 new commercial airline pilots and 238,000 new technicians in the Asia Pacific region through 2034.
“The demand for 464,000 new pilots and maintenance technicians is a large number, and it translates into challenging, high-tech career opportunities for those who are interested in aerospace,” said Sherry Carbary, vice president, Boeing Flight Services. “Boeing invests heavily in inspiring the next generation of pilots and technicians, and we continuously introduce students to our industry.”
Leading the region in projected demand for new pilots and technicians:
- China – 100,000 pilots and 106,000 technicians
- Southeast Asia – 57,000 pilots and 60,000 technicians
Other parts of the region will also continue to see long-term demand in the tens of thousands of pilots and technicians:
- South Asia – 40,000 pilots and 37,000 technicians
- Northeast Asia – 17,000 pilots and 22,000 technicians
- Oceania region – 12,000 pilots and 13,000 technicians
The Boeing Company, together with its auxiliaries, designs, develops, manufactures, sells, services, and supports commercial jetliners, military aircraft, satellites, missile defense, human space flight, and launch systems and services worldwide.
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