On Tuesday, XenoPort, Inc. (NASDAQ:XNPT)’s shares declined -28.08% to $4.84.
XenoPort, Inc. (XNPT) declared positive preliminary top-line results from its Phase 2 clinical trial of XP23829 as a potential treatment for moderate-to-severe chronic plaque-type psoriasis. XP23829 met its primary endpoint in both 800 mg once daily and 400 mg twice daily doses, demonstrating statistically noteworthy improvements in percent change from baseline to week 12 in Psoriasis Area and Severity Index (PASI) score. XP23829 is a patented prodrug of monomethyl fumarate (MMF) in a novel oral formulation that was designed to potentially offer physicians and patients an effective, better tolerated and easier to use therapeutic option to presently accessible fumarate products.
Richard Kim, M.D., chief medical officer of XenoPort, stated, “We believe these clinical data demonstrate for the first time that a MMF prodrug other than dimethyl fumarate (DMF) can be effective in reducing lesions in psoriatic patients. The magnitude of XP23829’s effect on the primary efficacy endpoint met our expectations for this relatively short duration trial and we are particularly encouraged by the results with 800 mg once-daily dosing. Based on what is known about fumarates, we believe that the efficacy of XP23829 is likely to improve with a more extended duration of treatment beyond 12 weeks. We are also happy with the safety and tolerability profile of XP23829 emerging from this study. We believe that this demonstration of efficacy, safety and tolerability of XP23829 could lead to a differentiated product in psoriasis. We also believe that there is potential for the observations from this study to read through to other potential indications such as multiple sclerosis (MS).”
XenoPort, Inc., a biopharmaceutical company, focuses on developing and commercializing a portfolio of product candidates for the treatment of neurological and other disorders. It offers HORIZANT (gabapentin enacarbil) extended-release tablets for the treatment of moderate-to-severe primary restless legs syndrome in adults and for the administration of postherpetic neuralgia in adults.
Zynga Inc (NASDAQ:ZNGA)’s shares gained 1.20% to $2.52.
Zynga ( ZNGA) is now one asset heavier. On Monday, the online games purveyor declared on its official company blog that it attained developer Rising Tide Games, a studio that concentrates on social casino titles. The terms of the acquisition were not revealed.
In the blog post, Zynga quoted Rising Tide Games’ co-CEO Mytal Olsha as saying, “I believe we can deliver fun, unique, Social Slots experiences to players around the world in the growing Social Casino space.” The purchase brings Olsha back into the fold, as she was formerly a Zynga executive — she left last year to assist start Rising Tide Games.
At the moment, Rising Tide Games has a single title on the market: Black Diamond Casino, a fresh release. It is presently accessible for download only in the U.S. Zynga’s purchase of the developer is not its first in the social casino games segment. In 2013, it bought Spooky Cool Labs, the studio that developed Hit It Rich! Slots. The segment has been a good one for Zynga. The company’s bookings for social casino games rose by 274% on a year-over-year basis in the second quarter of 2015.
Zynga Inc. develops, markets, and operates online social games as live services played on the Internet, social networking sites, and mobile platforms in the United States, Asia, and Europe. The company offers its online social games under the FarmVille, Words With Friends, Zynga Poker, Hit It Rich! Slots, CSR Racing, FarmVille 2: Country Escape, NFL Showdown, New Zynga Poker, New Words With Friends, Wizard of Oz Slots, Looney Tunes Dash!, CSR Classics, and Clumsy Ninja names. Its games are accessible on Facebook and other social netoperates, mobile platforms, and Zynga.com.
At the end of Tuesday’s trade, Bank of New York Mellon Corp (NYSE:BK)‘s shares surged 1.25% to $40.06.
Through the generosity of The Eugene F. Fay Trust, BNY Mellon has awarded operating support grants to 10 Boston-area nonprofits, providing them with critical funding for capacity-building activities. The Eugene F. Fay Trust Mini-Grants Program provides organizations with $5,000 grants for technical assistance and non-programmatic support aimed at strengthening the overall organization or a particular program. BNY Mellon is trustee of the Eugene F. Fay Trust and administers the mini-grants program.
The 2015 Eugene F. Fay Trust Mini-Grant awardees are:
- Asian American Civic Association – To convert and load legacy data into its new database, Efforts to Outcomes, which will allow AACA to better serve additional clients and track individual outcomes.
- Boston Chinatown Neighborhood Center – To purchase and install a new wireless router and firewall system, which will enhance BCNC’s efficiency, allow staff to spend more time on direct programming and enable BCNC to focus more on serving its clients.
- Ethos – To develop a three-year planned plan for its Boston Money Administration Program.
- FamilyAid Boston – To provide professional developmental trainings for newly promoted managers and support for high-performing administration staff in the organization.
- Horizons for Homeless Children – To enable Family Advocates to take part in developmental trainings to better equip them to assess and coach families and assist them access services on their way to becoming independent.
- Irish International Immigrant Center – To purchase technology and office furniture items that will streamline its operations and provide a more confidential and accurate process for meeting with and serving clients.
The Bank of New York Mellon Corporation, an investment company, provides financial products and services to institutions, corporations, and high net worth individuals in the United States and internationally. It operates through two segments, Investment Administration and Investment Services.
Whole Foods Market, Inc. (NASDAQ:WFM), ended its Tuesday’s trading session with 1.47% gain, and closed at $32.47.
Hagens Berman Sobol Shapiro LLP, a national investor-rights law firm, reminds investors of the October 5, 2015 lead plaintiff deadline in the securities fraud class action lawsuit filed against Whole Foods Market (WFM). If you have losses in Whole Foods securities during the Class Period contact Hagens Berman Partner Reed Kathrein,
Whole Foods Market, Inc. operates as a retailer of natural and organic foods. The company’s stores offer produce and floral, grocery, meat, seafood, bakery, prepared foods and catering, coffee, tea, beer, wine, cheese, nutritional supplements, vitamins, and body care products, in addition to lifestyle products, counting books, pet products, and household products.
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