On Wednesday, Shares of Gilead Sciences, Inc. (NASDAQ:GILD), gained 2.74% to $104.27.
Gilead Sciences, declared that a Phase 3 study evaluating its investigational fixed-dose combination of emtricitabine and tenofovir alafenamide (200/10 mg and 200/25 mg) (F/TAF) for the treatment of HIV-1 infection met its primary objective. The ongoing study was designed to explore the efficacy and safety of F/TAF-based regimens among virologically suppressed adult patients switching from HIV treatment regimens containing emtricitabine/tenofovir disoproxil fumarate (FTC/TDF) (Truvada®). At Week 48, the F/TAF-based regimens and the TDF-based regimens achieved similar rates of virologic suppression based on the proportion of patients with HIV RNA levels (viral load) of less than 50 copies/mL (94.3 percent for F/TAF-based regimens as compared to 93.0 percent for TDF-based regimens; difference in percentages: 1.3 percent, 95 percent CI: -2.5 percent to 5.1 percent).
Contrast to the TDF-based regimens, the F/TAF-based regimens demonstrated statistically noteworthy differences in mean bone mineral density (BMD) at the hip and spine (p<0.001) and in the median change in estimated glomerular filtration rate (eGFR) (p<0.001). General safety and discontinuation rates due to adverse events were comparable between the two arms. The most commonly stated adverse events comprised upper respiratory tract infection, diarrhea, nasopharyngitis, headache, and bronchitis. Both regimens were generally well tolerated. Gilead plans to submit these data for presentation at a scientific conference in 2016.
“For more than a decade, Truvada has been a cornerstone of HIV therapy, and the results of this and other recent trials demonstrate the potential of F/TAF to become a next-generation backbone,” said Norbert Bischofberger, PhD, Executive Vice President, Research and Development and Chief Scientific Officer, Gilead Sciences. “The results from this study reinforce the efficacy, in addition to the renal and bone safety advantages of TAF for patients who face a lifetime of treatment.”
Gilead Sciences, Inc., a biopharmaceutical company, discovers, develops, and commercializes medicines in areas of unmet medical need in North America, South America, Europe, and the Asia-Pacific.
Shares of Advanced Micro Devices, Inc. (NASDAQ:AMD), inclined 3.51% to $1.77, during its last trading session.
Top technologists from AMD (AMD) are detailing the engineering accomplishments behind the performance and energy efficiency of the new high-performance Accelerated Processing Unit (APU), codenamed “Carrizo,” and the new AMD Radeon™ R9 Fury family of GPUs, codenamed “Fiji,” at the prestigious annual Hot Chips symposium starting recently. The presentations will focus on new details of the high-definition video and graphics processing engines on the 6th Generation AMD A-Series APU (“Carrizo”), and the eight year journey leading to die-stacking technology and all-new memory architecture comprised on the latest top-of-the-line AMD Radeon™ Fury Series GPUs (“Fiji”) for 4K gaming and VR. Using a true System-on-Chip (SoC) design, 6th Generation AMD A-Series processors are designed to reduce the power consumed by the x86 cores alone by 40 percent,1 while providing substantial gains in CPU, graphics, and multimedia performance as compared to the preceding generation APU. The new AMD Radeon™ R9 Fury X GPU achieves up to 1.5x the performance-per-watt of the previous high-end GPU from AMD.
“With our new generation of APU and GPU technology, our engineering teams left no stone unturned for performance and energy efficiency,” said Mark Papermaster, chief technology officer at AMD. “Using innovative design for our APUs, we’ve vastly raised the number of transistors on-chip to improvement functionality and performance, implemented advanced power administration, and accomplished the hardware implementation of Heterogeneous System Architecture. For our latest GPUs, AMD is the first to introduce breakthrough technology in the form of die-stacking and High-Bandwidth Memory. The results are great products with very large generational performance-per-watt gains.”
The details will be shared in two symposium presentations. On August 24, Guhan Krishnan, AMD fellow, design engineering, will present “Energy efficiency in graphics and multimedia in 28nm ‘Carrizo’ APU.” This session will provide an in-depth view of the multitude of advancements resulting in superior performance, battery life, and user experiences on performance notebook and convertible form factors. In “AMD’s next Generation GPU and memory architecture” on August 25, Joe Macri, corporate vice president and product chief technology officer at AMD, will share the journey from inception to market that covered eight years and involved several key partners, in addition to provide architectural details behind the performance and efficiency of the new AMD Radeon R9 Fury line of GPUs.
Advanced Micro Devices, Inc. operates as a semiconductor company worldwide. The company’s products primarily comprise x86 microprocessors as an accelerated processing unit (APU), chipsets, discrete graphics processing units (GPUs), and semi-custom System-on-Chip (SoC) products.
Finally, Super Micro Computer, Inc. (NASDAQ:SMCI), ended its last trade with 0.16% gain, and closed at $24.81.
Super Micro Computer, has developed a turnkey scale-up high performance unified block and file storage solution optimized for high performance data-centric environments. Supermicro’s 2U Ultra SuperServer® integrates NexentaStor, Nexenta’s flagship Open Source-driven Software-Defined Storage (OpenSDS) platform combined with 2U SuperStorage featuring HGST’s Ultrastar® SSD800MH.B and Ultrastar SSD1600MM high-performance Flash-based storage delivers cluster solutions in 19TB, 38TB, 76TB and 115TB configurations. NexentaStor OpenSDS, designed for Enterprise class performance provides unified file (NFS and SMB), block (FC and iSCSI) storage services, and robust data administration functions for maximum data integrity and high availability. The all-SSD solution supports the most demanding mission-critical applications in physical or virtualized infrastructure environments.
“Supermicro’s best-in-class server, storage, and networking solutions optimized for Enterprise, Data Center and Cloud scale environments drive business growth and innovation,” said Wally Liaw, Sr. Vice President of Sales at Supermicro. “Partnership with Nexenta and HGST offers choices to our customers who are looking for high-performance all-flash SDS solutions and this highlights our strengths in advanced technology integration for high performance data workloads of any scale. This unified storage solution provides customers a scalable high IOPS storage infrastructure that delivers performance, reliability and cost effectiveness in addition to ease of administration with robust automation features.”
Super Micro Computer, Inc., together with its auxiliaries, develops and provides high performance server solutions based on modular and open-standard architecture. The company offers a range of server, storage, blade, workstation, and full rack solutions, in addition to networking devices, server administration software, and technology support and services.
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