During Wednesday’s Current trade, Shares of Seattle Genetics, Inc. (NASDAQ:SGEN), gain 3.64% to $50.42.
Seattle Genetics, Inc. (SGEN) declared the initiation of a phase 2 clinical trial evaluating ADCETRIS (brentuximab vedotin) in systemic lupus erythematosus (SLE, or lupus). Lupus is a chronic autoimmune disease in which the body’s own immune system overreacts and attacks healthy organs, causing inflammation, pain, permanent organ damage or death. ADCETRIS is an antibody-drug conjugate (ADC) directed to CD30, which is expressed on activated lymphocytes that are thought to play a key role in the development of autoimmune diseases, counting lupus. The trial is designed to assess the safety and activity of ADCETRIS in adult patients with lupus. ADCETRIS is presently not approved for the treatment of lupus.
The study is a phase 2 randomized, double-blind, placebo-controlled dose-escalation clinical trial. The primary objective is evaluation of the safety of ADCETRIS in adults with active lupus. In addition, the trial will evaluate the activity and pharmacokinetics of ADCETRIS in lupus. ADCETRIS will be administered every three weeks and about 40 patients will be enrolled at multiple centers in the United States.
Seattle Genetics, Inc., a biotechnology company, develops and commercializes antibody-based therapies for the treatment of cancer. The company is developing antibody-drug conjugates (ADCs), a technology designed to harness the targeting ability of antibodies to deliver cell-killing agents directly to cancer cells. Its lead product, ADCETRIS (brentuximab vedotin), is an ADC that is commercially accessible in about 50 countries, counting the United States, Canada, Japan, and members of the European Union for relapsed Hodgkin lymphoma (HL) and relapsed systemic anaplastic large cell lymphoma (sALCL) in partnership with Takeda Pharmaceutical Company Limited.
Shares of Barnes & Noble, Inc. (NYSE:BKS), declined -0.81% to $28.27, during its current trading session.
Barnes & Noble, Inc. (BKS) the nation’s largest retail bookseller and the leading retailer of content, digital media and educational products declared that it has expanded its selection of Graphic Novels and Manga to double the size at all stores nationwide. The company said the expansion is due to strong customer demand and the growing popularity of these genres. The expanded section features eye-catching signage on bookshelves that directs customers to series and characters they’ll want to know more about, making for easier browsing and discovery.
Barnes & Noble, Inc. operates as a content, commerce, and technology company in the United States. The company operates in three segments: B&N Retail, B&N College, and NOOK. It provides access to books, magazines, newspapers, and other content through its multi-channel distribution platform. The company sells trade books, counting hardcover and paperback consumer titles; mass market paperbacks, such as mystery, romance, science fiction, and other fiction; children’s books; eBooks and other digital content; NOOK products comprising NOOK 1st Edition, NOOK Wi-Fi 1st Edition, NOOK Color, NOOK Simple Touch, NOOK Tablet, NOOK Simple Touch with GlowLight, NOOK HD, NOOK HD+, NOOK GlowLight eReader devices, and related accessories; bargain books; magazines; gifts; cafe products and services; educational toys and games; music; and movies.
Polycom Inc (NASDAQ:PLCM), during its Wednesday’s current trading session gained 0.09% to $11.52.
Polycom, Inc. (PLCM) declared that Christopher M. Jones will join the company as President, Polycom Americas, on Aug. 3. In this role, Jones will be responsible for leading the company’s regional sales strategy and execution to drive customer success and profitable growth for Polycom and its partners.
Polycom, Inc. provides partnership solutions for voice, video, and content sharing. The company offers video, voice, and content-administration and content-sharing solutions, such as telepresence and conference room systems, home/work office solutions, applications for mobile devices, browser-based video collaboration, and cloud-delivered services, in addition to industry-specific solutions, counting specialized video carts and solutions for healthcare, education, and manufacturing. It also provides telepresence and video conferencing systems to incorporate high-definition (HD) data sharing and partnership into a video conference; peripherals and accessories; UC group devices primarily for the Skype for Business environment; and conference phones to conduct voice conference calls.
Finally, First Niagara Financial Group Inc. (NASDAQ:FNFG), gained 1.21%, to $9.60.
First Niagara Financial Group, Inc. (FNFG) declared that Peggy Yankovich joined the bank’s Treasury Administration group to lead its commercial card and payments business.
As Head of Commercial Card and Payments, Yankovich will lead all aspects of First Niagara’s commercial payments counting card-based solutions, product strategy, positioning, business administration and sales enablement.
The 28-year banking veteran joins First Niagara following eight years with HSBC Bank in New York City. Most recently, she served as Global Head of Commercial Card, responsible for creating, leading and executing HSBC’s strategy to launch and manage products and enhancements across North America, Latin America, Europe, Middle East and Asia. Formerly, she was HSBC’s North American Head of Commercial Card. She also worked at Bank of America for nine years, eventually becoming the company’s Commercial Card Payments Executive. Yankovich began her career at NationsBank in Dover, Del. in 1987.
First Niagara Financial Group, Inc. operates as the bank holding company for First Niagara Bank, N.A. that provides retail and commercial banking, and other financial services to individuals, families, and businesses. The company’s deposit products comprise savings and money market, and certificate of deposit accounts, in addition to municipal deposits. Its loan portfolio comprise commercial business loans; commercial real estate and multi-family lending products; residential real estate lending products; home equity lending products; indirect automobile lending products; credit cards; and other consumer loans, such as personal secured and unsecured loans, and overdraft lines of credit.
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