During Wednesday’s current trade, Medivation Inc (NASDAQ:MDVN)’s shares decline -1.07% to $110.64.
Medivation, Inc. ( MDVN) declared that data from a Phase 2 study evaluating the investigational use of enzalutamide as a single agent for the treatment of advanced androgen receptor (AR) positive, triple-negative breast cancer (TNBC) were presented during an oral abstracts session at the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago. The study met its primary endpoint and the abstract was also selected to be featured in the forthcoming ‘Best of ASCO’ meetings.
The Phase 2 open label single arm, multicenter trial enrolled 118 women with advanced TNBC in two stages. The primary endpoint of the trial was clinical benefit rate at 16 weeks (CBR16), defined as the proportion of women with a complete response (CR), partial response (PR) or stable disease for at least 16 weeks. Two patient populations were evaluated in this study: the Evaluable patient population had at least 10 percent of the cells in their primary tumor sample test positive for the AR and had at least one follow up tumor assessment, while the Intent-To-Treat population (ITT) received at least one dose of enzalutamide and their breast cancer had any amount of AR immunohistochemistry staining present. 75 patients met the criteria for the Evaluable population and a total of 118 patients were comprised of in the ITT population. There was no limit to the number of prior treatments received.
- In the 75 Evaluable patients, CBR16 was achieved in 35% (95% CI: 24-46) counting six CR/PR (8%). Clinical benefit rate at ≥ 24 weeks (CBR24) was achieved in 29% (95% CI: 20-41). The median progression-free survival (PFS) was 14.7 weeks (95% CI: 8.1-19.3).
- In the ITT population, CBR16 was achieved in 25% (95% CI: 17-33) counting seven CR/PR (6%). CBR24 was achieved in 20% (95% CI: 14-29). Median PFS was 12.6 weeks (95% CI: 8.1-15.7).
Medivation, Inc., a biopharmaceutical company, focuses on the development and commercialization of novel therapies to treat serious diseases in the United States. It offers XTANDI for the treatment of post-chemotherapy metastatic castration-resistant prostate cancer (mCRPC) patients.
Rackspace Hosting, Inc. (NYSE:RAX)‘s shares gain 0.28% to $38.88, during the current trading session Wednesday’s, hitting its highest level.
Rackspace Hosting, Inc. (RAX) declared it has won the 2015 Microsoft Hosting Partner of the Year Award. The company was honored among a global field of top Microsoft partners for demonstrating excellence in innovation and implementation of customer solutions based on Microsoft technology.
Awards were presented in several categories, with winners chosen from a set of more than 2,300 entrants from 108 different countries worldwide. Rackspace was recognized for providing outstanding solutions and services in Hosting Partner of the Year category. The Hosting Partner of the Year Award recognizes a partner that demonstrates solution innovation and exemplary commitment to engaging with Microsoft.
Rackspace Hosting, Inc., through its auxiliaries, provides cloud computing services and managing Web-based IT systems for small and medium-sized businesses and large enterprises worldwide. The company’s service offering combines hosting on dedicated hardware and on multi-tenant pools of virtualized hardware in a way that suits each customer’s requirements. Its public cloud services refer to pooled computing resources delivered on-demand over the Internet.
In a mid-morning trade, Kimco Realty Corp (NYSE:KIM)‘s shares plunge -0.26% to $23.01.
Kimco Realty Corp. (KIM) will declare its second quarter earnings on Tuesday, July 28, 2015 after market close. You are invited to listen to our quarterly earnings conference call, which will be broadcast live over the Internet on Wednesday, July 29, 2015 at 10:00 AM EDT.
Kimco Realty Corporation is an independent real estate investment trust. The firm invests in the real estate markets across North America. It is primarily engaged in acquisitions, development, and administration of neighborhood and community shopping centers. The firm also provides property administration services regarding the administration, leasing, operation, and maintenance of real estate properties. Kimco Realty Corporation was formed in 1966 and is based in New Hyde Park, New York with additional office all across North America.
Agria Corporation (ADR) (NYSE:GRO), during its Wednesday’s current trading session 0.67% gain and closed at $1.51.
Agria Corporation (NYSE: GRO) uncovered the appointment of Mr. Brent de Jong as Executive Director to the Company’s Board of Directors.
Mr. de Jong holds directorships with various publicly listed companies internationally and is based in Houston, Texas. Mr. de Jong was previously at Ashmore Investment Management Ltd. (“Ashmore”) (2002-2011), an emerging market fund manager with $65 billion in assets under management at the time of his departure. At Ashmore, Mr. de Jong served on the firm’s Investment Committee as the head of special situations and infrastructure investments (2009-2011) and also focused on special situation investments in Latin America and EMEA (2002-2009). During his time at Ashmore, he led a consortium of shareholders that founded AEI (formerly known as Ashmore Energy International), an owner and operator of more than 50 essential energy infrastructure assets in 19 countries with 15,000 employees at its peak. At AEI, Mr. de Jong served as the CEO from 2006-2007 and then as the Vice Chairman. Mr. de Jong negotiated the break up and sale of AEI’s assets in 2011.
Earlier in his career, Mr. de Jong worked at JP Morgan (1997-2002) in its financial institutions group in London, where he focused on M&A in the EMEA emerging markets, and in the structured finance group in New York. Mr. de Jong holds a bachelor’s degree in economics from Georgetown University.
Agria Corporation, together with its auxiliaries, operates as an agricultural company in China, South America, New Zealand, and Australia. It operates through three segments: Seed & Grain; Crop Protection, Nutrients, and Merchandise; and Rural Services. The Seed & Grain segment engages in the research and development, production, and sale of various seed products, counting forage, turf, maize, corn, cereal, and vegetable seeds; multiplication of seeds; and trading of seed and grain products internationally.
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