On Friday, Inovio Pharmaceuticals Inc (NASDAQ:INO)’s shares inclined 3.23% to $7.34.
Inovio Pharmaceuticals, Inc. (INO) declared that the first patient has been dosed in a phase I trial to evaluate safety and tolerability of PENNVAX(R)-GP, Inovio’s “universal” DNA vaccine for HIV. This human study is in partnership with the HIV Vaccine Trials Network (HVTN). The trial will measure immune responses following administration of the vaccine in four groups of healthy subjects receiving the vaccine with and without an immune activator (IL-12) and delivered into muscle or skin using Inovio’s CELLECTRA(R) delivery technology. This study is conducted by the HVTN and funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH).
Development of the PENNVAX-GP vaccine, which targets multiple clades of HIV—providing global coverage—has been funded through a $25 million NIAID contract awarded to Inovio and its collaborators. Earlier this year, Inovio and its collaborators were awarded a five-year $16 million Integrated Preclinical/Clinical AIDS Vaccine Development (IPCAVD) grant from NIAID. This new five-year program grant was awarded based on a peer-reviewed meritorious proposal by Dr. David Weiner, from the University of Pennsylvania and chair of Inovio’s scientific advisory board, and Inovio.
Inovio Pharmaceuticals, Inc., a clinical stage biopharmaceutical company, develops active DNA immunotherapies and vaccines in combination with proprietary electroporation delivery devices to prevent and treat cancers and infectious diseases. The company’s SynCon immunotherapy design has the ability to break the immune system’s tolerance of cancerous cells; and SynCon product design is also intended to facilitate cross-strain protection against known, in addition to new unmatched strains of pathogens, such as influenza.
Danaher Corporation (NYSE:DHR)’s shares gained 0.92% to $86.84.
Danaher Corporation (DHR) declared that it has priced a public offering of:
- $500 million principal amount of 1.650% senior notes due 2018 at an offering price of 99.866% of the principal amount;
- $500 million principal amount of 2.400% senior notes due 2020 at an offering price of 99.757% of the principal amount;
- $500 million principal amount of 3.350% senior notes due 2025 at an offering price of 99.857% of the principal amount; and
- $500 million principal amount of 4.375% senior notes due 2045 at an offering price of 99.784% of the principal amount.
Danaher anticipates to receive net proceeds, after deducting estimated expenses and the underwriters’ discounts and commissions, of about $1.98 billion. Danaher anticipates using the net proceeds from the offering to repay a portion of the commercial paper issued to finance a portion of the purchase price for Danaher’s recently closed acquisition of Pall Corporation. The offering is predictable to close on September 15, 2015, subject to customary closing conditions.
Citigroup, Barclays, Jefferies, J.P. Morgan, MUFG and Wells Fargo Securities are acting as joint book-running managers for the offering.
The offering is being made following an effective shelf registration statement on file with the U.S. Securities and Exchange Commission (the “SEC”).
Danaher Corporation designs, manufactures, and markets professional, medical, industrial, and commercial products and services worldwide. The company’s Test & Measurement segment provides test, measurement, and monitoring products that are used in electronic design, manufacturing, and technology development; hardware and software solutions to deploy, manage, and secure communication network technologies and services; and tools, toolboxes, and automotive maintenance equipment.
At the end of Friday’s trade, Duke Energy Corp (NYSE:DUK)‘s shares surged 0.89% to $68.34.
Duke Energy has been named to the Dow Jones Sustainability Index (DJSI) for North America for the 10th successive year.
In the electric utility sector, 17 North American companies were evaluated for the index, and four were selected.
Since its launch in1999, the DJSI has tracked the financial performance of corporate sustainability leaders worldwide.
In selecting the top performers in each business sector, the DJSI reviews companies on several general and industry-specific topics related to economic, environmental and social dimensions.
Among them: Corporate governance, environmental policy, climate strategy, human capital development and corporate citizenship.
Duke Energy Corporation, together with its auxiliaries, operates as an energy company in the United States and Latin America. It operates through three segments: Regulated Utilities, International Energy, and Commercial Power. The Regulated Utilities segment generates, transmits, distributes, and sells electricity in the Carolinas, Florida, Ohio, Kentucky, and Indiana; and transports and sells natural gas in southwestern Ohio and northern Kentucky.
Leggett & Platt, Inc. (NYSE:LEG), ended its Friday’s trading session with 0.36% gain, and closed at $44.06.
Leggett & Platt declared that David S. Haffner, the company’s Chief Executive Officer and Board Chair, will retire from the company and the Board on December 31, 2015. Karl G. Glassman, the company’s President and Chief Operating Officer, will assume the role of CEO on January 1, 2016.
Haffner has been the company’s CEO since 2006, and Chairman of the Board since 2013. Before assuming the role of CEO, he served as the company’s Chief Operating Officer for seven years and in numerous positions of increasing responsibility since he joined the company in 1983.
Leggett & Platt, Incorporated designs and produces a range of engineered components and products worldwide. The company’s Residential Furnishings segment offers innersprings and wire forms; steel mechanisms and hardware, springs and seat suspensions, steel tubular seat frames, bed frames and ornamental beds, and adjustable beds; and structural fabrics, carpet underlay materials, and geo components. This segment serves manufacturers of finished bedding products and upholstered furniture; retailers and distributors of adjustable and ornamental beds, bed frames, and carpet underlay; and contractors, landscapers, road construction companies, and government agencies using geo components. Its Commercial Fixturing & Components segment provides bases, columns, back rests, casters, and frames for office chairs and control devices; and private label finished furniture.
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