On Wednesday, Amgen, Inc. (NASDAQ:AMGN)’s shares declined -0.14% to $145.72.
Amgen (AMGN) and Dezima Pharma B.V. (Dezima) declared that the companies have reached a definitive acquisition agreement under which Amgen will acquire Dezima, a privately-held, Netherlands-based biotechnology company focused on developing innovative treatments for dyslipidemia. Dezima shareholders have approved the agreement.
Dezima’s lead molecule is TA-8995, an oral, once-daily cholesteryl ester transfer protein (CETP) inhibitor. In a Phase 2b clinical trial for dyslipidemia, TA-8995 reduced low-density lipoprotein cholesterol (LDL-C) by 45 to 48 percent contrast to baseline. LDL-C reduction was compriseent when TA-8995 was administered as monotherapy or in combination with statins. The most common adverse events were nasopharyngitis and headache.
Under the terms of the agreement, Amgen will pay $300 million in cash at closing and up to $1.25 billion in additional payments if certain development and sales milestones are achieved. Low single-digit royalties will be paid on net product sales above a certain threshold. The agreement is subject to customary closing conditions, counting regulatory approvals, and is predictable to close in the fourth quarter of this year. Following the completion of the transaction, Dezima Pharma, which originally licensed rights to TA-8995 from Mitsubishi Tanabe Pharma Corporation (MTPC), will become a wholly owned partner of Amgen. MTPC will receive from Dezima a portion of the upfront payment, future development and sales milestone payments, and royalties on net product sales if a certain threshold is reached. MTPC will also retain development and commercialization rights to TA-8995 in certain territories in Asia, counting Japan.
Amgen Inc., a biotechnology company, discovers, develops, manufactures, and delivers human therapeutics worldwide. It focuses for the treatment of illness in the areas of oncology, hematology, inflammation, bone health, nephrology, cardiovascular, and general medicine.
Yandex NV (NASDAQ:YNDX)’s shares dropped -3.54% to $11.16.
Yandex (YNDX), one of the largest European internet companies and the leading search provider in Russia, has developed a technology for active protection of Yandex.Browser users. Called ‘Protect’, it comprises of a set of mechanisms that provide protection from the most common online dangers: phishing, malware, and interception of personal data. Yandex’s new technology prevents potential threats rather than trying to repair the damage after it has been done.
Protect keeps users’ personal data safe when they use an open Wi-Fi network, for example, in a cafe or an airport. Such netoperates are widespread and convenient, but they can be dangerous because users’ information can be easily intercepted. Protect routes Yandex.Browser traffic through a protected server, so that intercepting the data is impossible. The technology also blocks phishing sites — resources disguised as social netoperates or internet banking sites with the purpose of intercepting users’ personal data. If a user enters their login and password on such a site, Protect blocks the transmission of the data and warns of the danger. Protect also makes sure users do not go to sites with malicious code and automatically checks files downloaded from the internet for any viruses. If a file turns out to be dangerous, Protect does not allow it to be opened and harm the user’s device. The technology is described in more detail on Yandex’s blog (in Russian).
Yandex N.V. operates an Internet search engine in Russia and internationally. The company offers search, location-based, personalized, and mobile services that enable users to find information, and communicate and connect over the Internet from desktops and mobile devices; and localized homepages for specific geographic markets .
At the end of Wednesday’s trade, NiSource Inc. (NYSE:NI)‘s shares surged 0.69% to $17.44.
NiSource Inc. (NI) was named to the Dow Jones Sustainability Index (DJSI) North America in recognition of the company’s sustainable business practices and performance for the second successive year.
The DJSI North America Index and respective subsets track the performance of the top 20 percent of the 600 largest Canadian and United States companies in the S&P Global Broad Market Index. In the Multi and Water Utilities category, 14 North American companies were evaluated and four were selected. Since its launch in 1999, NiSource has been named to the DJSI nine times.
Performance highlights from NiSource’s latest Sustainability Report comprised of:
- Reliability and access through modern infrastructure:In 2014, NiSource invested more than $2.2 billion in modern pipes, wires and systems across our operations to continue to provide safe and reliable service for our customers.
- Customer savings:Through energy efficiency programs across NiSource’s utilities, customers saved about $16 million.
- Giving back:In 2014, NiSource donated about $6.2 million to organizations that are working to make a difference in communities across its service territories.
NiSource Inc., an energy holding company, provides natural gas, electricity, and other products and services in the United States. The company offers natural gas service and transportation to residential, commercial, and industrial customers; generates, transmits, and distributes electricity; and provides wholesale and transmission transaction services.
Net Element International Inc (NASDAQ:NETE), ended its Wednesday’s trading session with -3.16% loss, and closed at $0.184.
Net Element, Inc. ( NETE) a provider of global mobile payment technology solutions and value-added transactional services declared that it has closed on $1.59 million of insider financing.
As part of the insider financing, the Company sold 11,357,143 common shares to Kenges Rakishev, Chairman of the Company’s board of directors; Oleg Firer, Company’s CEO and director; Steven Wolberg, Company’s Chief Legal Officer; William Healy, a director of the Company and certain other investors. The Company also issued to the investors options to purchase common shares. The shares, the options and the shares issuable upon exercise of the options are subject to Rule 144 restrictions. The net proceeds of the offering will be used to fund the Company’s working capital.
Net Element, Inc., a global payments-as-a-service, operates as a technology provider with an integrated mobile and transactional services platform serving emerging market clients. The company, through its partner, TOT Group, Inc., operates Unified Payments that processes cashless transactions for card-present or card-not-present transactions, counting point-of-sale (POS), mobile POS (mPOS), EMV, near field communication, Apple Pay, Internet businesses, service-oriented businesses, and mail order/telephone order merchants, in addition to processes other cashless transactions, counting checks and direct debits.
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