On Monday, Shares of AEterna Zentaris Inc. (USA) (NASDAQ:AEZS), gained 13.52% to $0.0999.
AEterna Zentaris, declared that its lead oncology compound, zoptarelin doxorubicin (formerly AEZS‑108), met the primary end-point of the investigator-driven and sponsored Phase 2 clinical trial in Castration and taxane Resistant Prostate Cancer (CRPC) and demonstrated good tolerability. The primary endpoint was Clinical Benefit (CB) defined as remaining progression-free by RECIST and Prostate Specific Antigen (PSA) after treatment for 12+ weeks.
Results were presented this morning by lead investigator, Jacek Pinski , MD, PhD, of the USC Norris Comprehensive Cancer Center, during a poster session at the 18th ECCO – 40th ESMO European Cancer Congress in Vienna, Austria .
Study Design
This was a single-arm Simon Optimum design Phase 2 study of zoptarelin doxorubicin in 25 patients with CRPC. Patients received zoptarelin doxorubicin (210 mg/m2) intravenously over 2 hours, every 3 weeks. The primary endpoint was CB, defined as remaining progression-free by RECIST and PSA after treatment for 12+ weeks. Secondary endpoints were progression free survival (PFS), best overall response, toxicity, pain and overall survival (OS).
Aeterna Zentaris Inc. is a Canada based biopharmaceutical company engaged in developing novel treatments in oncology and endocrinology. The Company currently has three wholly owned direct and indirect subsidiaries, Aeterna Zentaris GmbH (AEZS Germany), Zentaris IVF GmbH, a wholly owned subsidiary of AEZS Germany, and Aeterna Zentaris, Inc.
Shares of Annaly Capital Management, Inc. (NYSE:NLY), declined -1.88% to $9.93, during its last trading session.
The Board of Directors of Annaly Capital Management declared the third quarter 2015 common stock cash dividend of $0.30 per common share. This dividend is payable October 30, 2015, to common shareholders of record on September 30, 2015. The ex-dividend date is September 28, 2015.
Annaly Capital Management, Inc. is a mortgage real estate investment trust (REIT). The Company uses its capital coupled with borrowed funds to invest in real estate related investments, earning the spread between the yield on its assets and the cost of its borrowings.
Shares of Caterpillar Inc. (NYSE:CAT), declined -1.82% to $63.79, during its last trading session.
Building on its 90-year history of providing unmatched product support around the world, Caterpillar Inc. (CAT) recently declared a reorganization in its dealer and customer support divisions. These changes are designed to improve and speed the delivery of customer support while simplifying the way Caterpillar interacts with its global dealer network.
The company is also placing added executive office emphasis on three planned initiatives – data analytics, digital and innovation capabilities; Lean Transformation; and the Across the Table initiative. Having this additional, executive office focus complements the new structure of Caterpillar’s customer and dealer-facing divisions.
Mining Division Changes
As formerly declared, Chris Curfman, vice president with responsibility for Caterpillar’s Mining Sales & Support Division is retiring, effective December 31, 2015. His division will be integrated into the existing Global Mining machine business divisions. Bringing product, operations, sales and marketing organizations together in both the surface and underground mining applications aligns well with our customers and will also enable a more effective cost structure in a challenging mining environment.
The surface mining sales and support teams will join the Hauling & Extraction Division, which will be renamed the Surface Mining & Technology Division, led by Caterpillar Vice President Tom Bluth.
Caterpillar Inc. is a manufacturer of construction and mining equipment, diesel and natural gas engines, industrial gas turbines and diesel-electric locomotives. The Company principally operates through its three product segments: Resource Industries, Construction Industries, and Energy & Transportation.
Finally, JetBlue Airways Corporation (NASDAQ:JBLU), ended its last trade with -4.43% loss, and closed at $25.48.
After successfully launching the first Havana-bound flight on a major airline from New York since travel restrictions were eased this year, JetBlue (JBLU) and Cuba Travel Services (CTS) recently declared the addition of a second JetBlue charter flight connecting the two cities with nonstop service. The expansion of the JetBlue-CTS plan comes shortly after the U.S. further eased restrictions by allowing approved travelers to Cuba to travel with close relatives.
The roundtrip charter flight between New York’s John F. Kennedy International Airport (JFK) and Havana’s José Martí International Airport (HAV) will operate every Tuesday starting December 1, 2015. The existing JetBlue-CTS flight operates every Friday, giving New York customers more flexibility in their travel plans.
JetBlue has doubled its number of charter flights to Cuba since travel restrictions have eased, and is the only major airline operating charter flights from New York.
JetBlue Airways Corporation is a passenger carrier company. The Company provides air transportation services across the United States, Caribbean and Latin America. The Company operates Airbus A321, Airbus A320 and EMBRAER 190 aircraft types.
DISCLAIMER:
This article is published by www.wsnewspublishers.com. The Content included in this article is just for informational purposes only. All information used in this article is believed to be from reliable sources, but we make no representations or warranties of any kind, express or implied, about the completeness, accuracy, or reliability with respect to this article.
All visitors are advised to conduct their own independent research into individual stocks before making a purchase decision.
Information contained in this article contains forward-looking information within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, counting statements regarding the predictable continual growth of the market for the corporation’s products, the corporation’s ability to fund its capital requirement in the near term and in the long term; pricing pressures; etc.
Any statements that express or involve discussions with respect to predictions, expectations, beliefs, plans, projections, objectives, aims, assumptions, or future events or performance may be forward looking statements. Forward-looking statements are based on expectations, estimates, and projections at the time the statements are made that involve a number of risks and uncertainties, which could cause actual results or events to differ materially from those presently anticipated. Forward looking statements may be identified with such words as expects, will, anticipates, estimates, believes, or by statements indicating certain actions may, could, should/might occur.
